Sertraline (Zoloft) For ADHD: Evidence, Useful Information & More

ADHD can make your brain feel scattered. Image by atlascompany on Freepik

Sertraline (Zoloft) For ADHD

This is a summary of the available information about taking Sertraline for ADHD. 

ADHD stands for attention deficit and hyperactivity disorder, and it is one of the most common neurodevelopmental. It's first diagnosed in childhood, albeit the symptoms frequently persist into adulthood. Individuals with ADHD often have of difficulties controlling impulsive behavior and maintaining attention, as well presenting with overly active behavior.

Sertraline is the active substance of well-known medicines such as 'Zoloft'. It belongs to a group of psychiatric medications called SSRIs. The medication acts by blocking the reuptake of serotonin in the brain synapses, increasing the effect of serotonin on the brain.

Provided information is not individual medical advice. Remember to always consult with your physician before starting any medications or if you're experiencing problems with your current medication. 

Current Evidence

• There is no FDA approval for using Sertraline for ADHD.  

• However, the prevalence rate of attention deficit and hyperactivity disorder among adults with major depression is 9.4%.

• Approximately 32.7% of those diagnosed with childhood ADHD suffers from recurrent depression during their lifetime.

• SSRIs, such as Sertraline, are often the first choice of treatment when treating patients with ADHD suffering from comorbid depression.

Treatment with Sertraline (Zoloft) for ADHD

• It is not advised to use Sertraline for ADHD in the absence of comorbid depression due to the lack of convincing evidence supporting any positive effect on the behavioral symptoms of ADHD.

Useful Information

• First-line is treatment of ADHD is pharmacotherapy with stimulant medication, e.g. Methylphenidate.

• The main strategy for treating adult patients with ADHD and comorbid depression is a combination of stimulant and antidepressant medications. SSRIs are generally well-tolerated and pose a low risk of potential drug interaction with stimulants.

• Adults suffering from ADHD with comorbid anxiety primarily benefit from stimulant pharmacotherapy. In most people with ADHD, anxiety symptoms do not worsen when using stimulant medication.
  

Author: J. Martin, M.D. 
Last updated: August 30, 2023

Disclaimer: The information provided is intended for general informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider, such as a physician, before starting any new treatment or making changes to your existing treatment plan. Individual responses to treatment may vary, and a healthcare professional can provide personalized guidance based on your specific needs and circumstances. If you are experiencing severe or persistent symptoms of disease seek immediate medical attention.